CYP51

CYP isoenzymes
++ = mitochondrial
# = found in lung tissue
CYP51 1 subfamily, 1 gene, 2 pseudogenes
(lanosterol 14-alpha demethylase)
Isoenzyme Substrates Inducer Inhibitor Alleles Effects (alleles, interactions)
CYP51
{Marked evolutionary conservation!}
lanosterol (makes cholesterol) ? ketoconazole, itraconazole; oxysterols ? (human CYP51 may be partially inhibited by azole antifungals)

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Last update 2000-1-22 Author jo@anaesthetist.com